Recently, researchers at National Nanoscience Center Jiang Xingyu, researcher Zhang Wei and Dr. Yang Mingzhu have developed a large-scale manufacturing method of barcoded paper-based chips and a barcode reader that can read out the results through paper stacking and cutting technology Multiple detection methods for the new features of traditional materials (paper) and the development of new applications provide ideas. Relevant research findings "Skiving stacked sheets of paper into test paper for rapid and multiplexed assay" were published online by Science Advances on December 1, 2017. Paper Stacking and Machining Technologies for Precision Machining and Large Scale Manufacturing of Bar Coded Paper-Based Die Paper-based chips because of its detection speed, easy to operate, portable and low cost advantages, is widely used in crude laboratories and resource-poor areas. However, the processing of micro-reaction channels on paper-based chips still rely on such technologies as photolithography, spray wax printing, ink jet printing, screen printing and plasma etching. The above technologies not only require sophisticated equipment, but also have low processing efficiency and difficulty in realizing paper Large-scale manufacturing base chip. In addition, the test results readout and data storage mostly rely on manual operation, not only inefficient there is a certain error rate. Jiang Xingyu task force will be one-dimensional bar code encoding for a variety of biomarkers to achieve multiple test results and efficient reading and input; the use of paper thickness simulation bar code wide and narrow cells, do not rely on any sophisticated equipment , Which realizes the accurate processing of the barcode in the chip. The large-scale manufacturing of the barcoded paper-based chip is realized by using the paper cutting technology. The detection and analysis system has a wide range of applications, fast detection speed, simple detection and readout operation and high efficiency, and provides a completely new method for real-time inspection. Bar code chip processing technology for large-scale paper-based chip manufacturing has opened up a whole new way. The research will also promote the application of paper-based chips in nucleic acid testing, drug screening and cell behavior research. The research was further expanded by Jiang Xingyu's research group (Lab Chip, 17,3874,2017; Anal Chem, 87,900,2015) and won the honorary titles of National Natural Science Foundation of China, National Major Scientific Instruments and Equipment Development Project and Chinese Academy of Sciences "Innovation Team International Partner Program" and other projects support. Hydraulic Assembly,High Precision Hydraulic Assembly,Hydraulic Lock High Precision,Hydraulic Safety Lock Huai'an Youbang Hydraulic Machinery Co., Ltd. , https://www.yb-hydraulic.com