On November 2, Saltigo, a subsidiary of Germany's LANXESS, announced that it has applied the palladium-catalyzed cross-coupling reaction, the leading technology that won the Nobel Prize in Chemistry this year, to the industrial sector.
Palladium-catalyzed cross-coupling reactions have become an important cornerstone of contemporary organic synthesis chemistry. Using this technology, one can economically produce a variety of active pharmaceutical ingredients, natural substances and other organic molecules with complex structures. Each year, Saltigo receives a number of customer consultations on catalytic cross-coupling reactions, and the number is on a clear upward trend. A prerequisite for successful cross-coupling reactions to achieve industrial applications is to optimize the catalytic system, especially the ligands. A great advantage of the palladium catalyzed coupling reaction is that when these reactions are used in industrial production, the scale-up will not become a problem relatively. In addition, when planning a synthesis project, Saltigo not only examines the modern catalytic process, but also refers to the traditional synthesis route, and ultimately provides customers with the optimal synthesis scheme.

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